Posted on | CategoriesDepartment of Medicinal Chemistry / Drug Discovery | PI: Raphael Franzini, PhD

Developing New Chemical Reactions that Can Be Performed in Living Cells

The development of bioorthogonal chemical reactions—chemical reactions that can be conducted in living cells—has been one of the most significant areas of advancement in chemistry in recent years. Franzini and colleagues have developed a series of highly efficient chemical reactions, termed “dissociative bioorthogonal reactions”, that do just that. Continue reading → Developing New Chemical Reactions that Can Be Performed in Living Cells
Posted on | CategoriesDepartment of Biochemistry / Fundamental Biology | PI: Janet Iwasa, PhD

Animation of the HIV Life Cycle

Atomically accurate molecular animations provide a unique opportunity for generating and testing new mechanistic hypotheses and promoting scientific communication and public outreach. Iwasa is a leader in the creation of sophisticated, dynamic 3D visualizations of biological processes. Continue reading → Animation of the HIV Life Cycle
Posted on | CategoriesDepartment of Human Genetics / Department of Pathology / Genomics | PI: Robert Schlaberg, MD , Gabor Marth, DSc , Mark Yandell, PhD & Karen Eilbeck, PhD

Rapid Identification of Microbial Pathogens

The rapid identification of microbial pathogens is critical for timely and successful treatments. Improved capabilities in pathogen identification were the focus of a collaboration between physicians and scientists in the departments of Biomedical Informatics, Human Genetics, and Pathology. Continue reading → Rapid Identification of Microbial Pathogens