Posted on | CategoriesBiochemistry / School of Medicine | PI: Tyler Starr, PhD

Evolution-Resistant Antibodies

Before vaccines were available in the first years of the COVID-19 pandemic, researchers had engineered antibodies that could block SARS-CoV-2, the virus that causes the disease, to prevent infection or reduce the severity of illness. But as the virus evolved, these drugs stopped working. Antibodies work by binding specific sites on the virus. Antibiotic resistance arises when mutation causes those sites to change. Continue reading → Evolution-Resistant Antibodies

Continue reading → Evolution-Resistant Antibodies
Posted on | CategoriesNeurology / School of Medicine | PI: Jim Heys, PhD

The Brain’s Medial Entorhinal Cortex Keeps Track of Time

Clocks are essential for keeping us in sync with the rhythms of the world, but we also rely our brain’s own awareness of the passage of time. Many different parts of the brain are involved in timekeeping, capturing information about time in patterns of neural activity, then using that information to make sense of events and coordinate actions. When injury or disease damages that circuitry, it can skew the way we remember the past and make it harder to plan for the future… Continue reading → The Brain’s Medial Entorhinal Cortex Keeps Track of Time

Continue reading → The Brain’s Medial Entorhinal Cortex Keeps Track of Time
Posted on | CategoriesCollege of Nursing | PI: Mollie R. Cummins, PhD, RN, FAAN, FACMI

Telemedicine Reduces Health Care’s Carbon Footprint

Global climate change has real consequences for human health. Rising temperatures, shifting precipitation patterns, and extreme weather increase food and water insecurity, spread infectious disease, and put people at greater risk. Health care systems are responding by delivering quality care while also reevaluating their own climate impact. Continue reading → Telemedicine Reduces Health Care’s Carbon Footprint

Continue reading → Telemedicine Reduces Health Care’s Carbon Footprint
Posted on | CategoriesNeurology / School of Medicine | PI: Stefan M. Pulst, MD

Identification of GGC Expansion as a Basis for SCA4 Movement Disorder

Spinocerebellar ataxia type 4 (SCA4) is a rare movement disorder whose symptoms begin in adolescence or adulthood, usually with difficulty walking and balancing. Affected individuals may go on to experience muscle weakness, lose sensation in their hands and feet, and lose their reflexes… Continue reading → Identification of GGC Expansion as a Basis for SCA4 Movement Disorder

Continue reading → Identification of GGC Expansion as a Basis for SCA4 Movement Disorder
Posted on | CategoriesNeurobiology / School of Medicine | PI: Jason Shepherd, PhD

PNMA2 Forms Immunogenic Non-Enveloped Virus-Like Capsids Associated with Paraneoplastic Neurological Syndrome

For people with a rare cancer-associated condition called paraneoplastic syndrome, sudden memory loss, loss of coordination, or other neurological symptoms are often the first sign that a tumor is growing somewhere in the body. The symptoms are caused by the immune system’s response to it. It turns out that some tumors produce brain proteins… Continue reading → PNMA2 Forms Immunogenic Non-Enveloped Virus-Like Capsids Associated with Paraneoplastic Neurological Syndrome

Continue reading → PNMA2 Forms Immunogenic Non-Enveloped Virus-Like Capsids Associated with Paraneoplastic Neurological Syndrome