Posted on | CategoriesObstetrics & Gynecology / Population Health / Prevention / School of Medicine | PI: Robert M. Silver, MD & Torri D. Metz, MD, MS

Risks of Cannabis During Pregnancy

Cannabis use is increasing among reproductive age females. However, the effects of cannabis use on pregnancy and pregnancy outcomes remains largely unknown. Torri Metz, MD, MS, vice chair of research of obstetrics and gynecology, and Robert Silver, MD, professor and chair of obstetrics and gynecology, examined if cannabis use during pregnancy was associated with adverse … […] Continue reading → Risks of Cannabis During Pregnancy Continue reading → Risks of Cannabis During Pregnancy

Continue reading → Risks of Cannabis During Pregnancy
Posted on | CategoriesDrug Discovery / Prevention | PI: Micah J. Drummond, PhD

Diabetes Drug Protects Against Muscle Loss

As we get older, it can be harder to bounce back from injury or prolonged periods of bed rest. That’s partly because it takes older adults longer to rebuild muscles that have atrophied due to disuse. The resulting weakness can limit mobility and put people at risk for falls, hospitalization, and even chronic disease. Encouragingly, it may be possible to protect older adults against muscle loss with a drug that millions of people already take. Continue reading → Diabetes Drug Protects Against Muscle Loss
Posted on | CategoriesCardiovascular | PI: TingTing Hong, MD, PhD & Robin M. Shaw, MD, PhD

Regulation and Remodeling of Membrane Microdomains of Cardiomyocytes During Heart Failure Progression

At U of U Health, scientists are learning how the molecular organization of heart cells changes as heart failure progresses, and using that knowledge to pioneer potential gene therapy for heart disease. Continue reading → Regulation and Remodeling of Membrane Microdomains of Cardiomyocytes During Heart Failure Progression
Posted on | CategoriesPopulation Health / Population Health Sciences / Prevention / School of Medicine | PI: Adam Bress, PharmD

Uncovering Disparities that Impact Heart Health

About 40 million adults in the United States take statin drugs to reduce their risk of heart disease and stroke. The drugs, which lower levels of LDL cholesterol, are considered safe for most people, and for many, their potential benefits are high. Many people who might benefit from statins, however, aren’t taking them. Graduate student … […] Continue reading → Uncovering Disparities that Impact Heart Health Continue reading → Uncovering Disparities that Impact Heart Health

Continue reading → Uncovering Disparities that Impact Heart Health
Posted on | CategoriesBiochemistry / College of Health / Nutrition & Integrative Physiology / School of Medicine | PI: Jared P. Rutter, PhD & Kevin Hicks, PhD

Finding Inspiration for Drug Development in Metabolic Regulators

The metabolic pathways that shape how our bodies use nutrients and energy are under constant adjustment, with metabolites pay a key role in managing their function and activity. There are thousands of metabolites inside our cells, and surprisingly little is known about how most of them interact with other cellular components, even though when these interactions with proteins are disrupted, it can leave us more vulnerable to disease. Continue reading → Finding Inspiration for Drug Development in Metabolic Regulators
Posted on | CategoriesBiochemistry / School of Medicine | PI: Minna Roh-Johnson, PhD

Transferred Mitochondria Accumulate Reactive Oxygen Species, Promoting Proliferation

Cancer cells don’t act on their own. Their behavior is influenced by neighboring cells, which sometimes help them grow and spread. For instance, immune cells called macrophages patrol the body, engulfing and destroying potential threats. But when they interact with tumors, they can often produce signals that drive the disease. Continue reading → Transferred Mitochondria Accumulate Reactive Oxygen Species, Promoting Proliferation