Posted on | CategoriesImmunology, Inflammation, Infectious Disease / Pathology | PI: Ryan O'Connell, PhD

MicroRNA Regulation of Inflammation and Immunity

MicroRNAs provide a crucial level of control for cell development and function through their post-transcriptional regulation of gene expression. Their importance is highlighted by their diverse functions in a range of cell types, including immune cells. Continue reading → MicroRNA Regulation of Inflammation and Immunity
Posted on | CategoriesBiochemistry / Diabetes and Metabolism | PI: Jared P. Rutter, PhD

Sensing and Regulating Cellular Energy Production

Cells must decide when to expand mitochondrial capacity to accommodate increased energy demands. Rutter, Winge, and colleagues have shown that the ancient mitochondrial fatty acid synthesis system has a profound and unexpected regulatory role in driving mitochondrial biogenesis. Continue reading → Sensing and Regulating Cellular Energy Production