Posted on | CategoriesCollege of Pharmacy / Molecular Pharmaceutics | PI: Mei Koh, PhD

How a Key Protein May Protect the Liver from Cancer Caused by Fatty Liver Disease

Liver cancer is one of the leading causes of cancer deaths worldwide. In the United States, rising rates of liver cancer have been tied to an increased prevalence of metabolic dysfunction–associated steatotic liver disease (MASLD), a condition in which excess fat accumulates in the liver. Continue reading → How a Key Protein May Protect the Liver from Cancer Caused by Fatty Liver Disease

Continue reading → How a Key Protein May Protect the Liver from Cancer Caused by Fatty Liver Disease
Posted on | CategoriesNeurobiology / School of Medicine | PI: Jason Shepherd, PhD

PNMA2 Forms Immunogenic Non-Enveloped Virus-Like Capsids Associated with Paraneoplastic Neurological Syndrome

For people with a rare cancer-associated condition called paraneoplastic syndrome, sudden memory loss, loss of coordination, or other neurological symptoms are often the first sign that a tumor is growing somewhere in the body. The symptoms are caused by the immune system’s response to it. It turns out that some tumors produce brain proteins… Continue reading → PNMA2 Forms Immunogenic Non-Enveloped Virus-Like Capsids Associated with Paraneoplastic Neurological Syndrome

Continue reading → PNMA2 Forms Immunogenic Non-Enveloped Virus-Like Capsids Associated with Paraneoplastic Neurological Syndrome
Posted on | CategoriesInternal Medicine / School of Medicine | PI: Nareej Agarwal, MD

Talazoparib Plus Enzalutamide Increases Survival Rates in Men with Metastatic Castration-resistant Prostate Cancer

Prostate cancer is the second most common cause of cancer deaths for men in the United States. Worldwide, more than a million new cases are diagnosed each year. Treatment often includes drugs that rein in the cancer by blocking hormones that spur its growth. But as the disease progresses, many tumors become less sensitive to this type of treatment. Continue reading → Talazoparib Plus Enzalutamide Increases Survival Rates in Men with Metastatic Castration-resistant Prostate Cancer

Continue reading → Talazoparib Plus Enzalutamide Increases Survival Rates in Men with Metastatic Castration-resistant Prostate Cancer
Posted on | CategoriesBiochemistry / School of Medicine | PI: Minna Roh-Johnson, PhD

Transferred Mitochondria Accumulate Reactive Oxygen Species, Promoting Proliferation

Cancer cells don’t act on their own. Their behavior is influenced by neighboring cells, which sometimes help them grow and spread. For instance, immune cells called macrophages patrol the body, engulfing and destroying potential threats. But when they interact with tumors, they can often produce signals that drive the disease. Continue reading → Transferred Mitochondria Accumulate Reactive Oxygen Species, Promoting Proliferation

Continue reading → Transferred Mitochondria Accumulate Reactive Oxygen Species, Promoting Proliferation