Posted on | CategoriesNeurology / School of Medicine | PI: Stefan M. Pulst, MD

Identification of GGC Expansion as a Basis for SCA4 Movement Disorder

Spinocerebellar ataxia type 4 (SCA4) is a rare movement disorder whose symptoms begin in adolescence or adulthood, usually with difficulty walking and balancing. Affected individuals may go on to experience muscle weakness, lose sensation in their hands and feet, and lose their reflexes... Continue reading → Identification of GGC Expansion as a Basis for SCA4 Movement Disorder
Posted on | CategoriesHealth and Disease / Neurology | PI: Stefan M. Pulst, MD & Daniel R. Scoles, PhD

Therapy for ALS

Amyotrophic lateral sclerosis (ALS) is a catastrophic degeneration of the nervous system with great need for disease-modifying treatments. Stefan Pulst, MD, and his collaborator Daniel Scoles, PhD, were studying a lesser-known but similarly dire condition (spinocerebellar ataxia 2, SCA2) when they identified a gene relevant to both diseases. Continue reading → Therapy for ALS