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The CRISPR/Cas9 DNA editing system offers the potential for revolutionary new treatments of genetic diseases. Pioneering work by Carroll set the stage for this revolution by characterizing how cells detect and repair double-stranded DNA breaks. Continue reading → Correcting the Genetic Error in Sickle Cell Disease
Continue reading → Correcting the Genetic Error in Sickle Cell DiseaseDeficient or excess immune system activities cause many human diseases. To understand the mechanisms of immune injury and their links to pathologic clotting, University of Utah Health investigators Christian Yost, MD, Guy Zimmerman, MD, and colleagues defined features of neutrophil extracellular traps (NETs). Continue reading → Inhibiting Neutrophil Extracellular Traps (NETs) in Immune Injury and Pathologic Clotting
Continue reading → Inhibiting Neutrophil Extracellular Traps (NETs) in Immune Injury and Pathologic Clotting