A New Form of Glutamate Signaling Discovered in Migraine

Using two-photon microscopy, K.C. Brennan, MD, and colleagues discovered unusual activity of the excitatory neurotransmitter glutamate in mice carrying a mutated gene identified from a family with inherited migraine. Continue reading → A New Form of Glutamate Signaling Discovered in Migraine

Continue reading → A New Form of Glutamate Signaling Discovered in Migraine

Neuronal Circuits that Modulate Pain and Defensive Responses

Understanding pain-processing mechanisms and the neural circuits involved is central to developing new therapeutic strategies for the treatment of pain. The Douglass lab investigated brain regions that modulate behavioral responses to noxious stimuli in zebrafish. Continue reading → Neuronal Circuits that Modulate Pain and Defensive Responses

Continue reading → Neuronal Circuits that Modulate Pain and Defensive Responses