Research Statement

In 2020, Dr. Hong was recruited to the University of Utah to continue her research program focusing on understanding the regulation and remodeling of membrane microdomains of cardiomyocytes during heart failure progression. The Hong Lab studies how cardiomyocyte surface microdomains are organized to concentrate ion channels and signaling proteins for proper function and regulation in normal and failing hearts. The research includes the mechanisms of scaffolding protein and cytoskeleton-based maintenance of membrane structures and subdomains important in calcium signaling, turnover mechanisms of microdomains, and the mechanisms of heart failure progression. The goal is to identify, at the bench, new molecular and cellular targets that can be translated to develop new therapeutic tools for clinical management of heart failure.

The Hong Laboratory

Cardiovascular Pharmacology & Toxicology Research Program