Posted on | CategoriesCollege of Pharmacy / Molecular Pharmaceutics | PI: Mei Koh, PhD

How a Key Protein May Protect the Liver from Cancer Caused by Fatty Liver Disease

Liver cancer is one of the leading causes of cancer deaths worldwide. In the United States, rising rates of liver cancer have been tied to an increased prevalence of metabolic dysfunction–associated steatotic liver disease (MASLD), a condition in which excess fat accumulates in the liver. Continue reading → How a Key Protein May Protect the Liver from Cancer Caused by Fatty Liver Disease

Continue reading → How a Key Protein May Protect the Liver from Cancer Caused by Fatty Liver Disease
Posted on | CategoriesCollege of Health / Health & Kinesiology | PI: Genevieve Albouy, PhD

Boosting Memory During Sleep

While our bodies rest, our brains keep learning, replaying experiences to solidify our memories and improve our future performance. Genevieve Albouy, PhD, an associate professor in the Department of Health & Kinesiology at the University of Utah College of Health, studies this process of memory consolidation, looking for ways learning might be enhanced. Continue reading → Boosting Memory During Sleep

Continue reading → Boosting Memory During Sleep
Posted on | CategoriesInternal Medicine / School of Medicine | PI: Mary Jo Pugh, PhD, RN

Brain and Body Impacts of TBI

Traumatic brain injuries (TBIs) are injuries that affect the function of the brain—and millions of people worldwide have experienced at least one. Bumps and blows from falls and collisions, as well as gunshots and explosive blasts, can cause TBIs. When a TBI is mild, the initial headaches, confusion, and memory loss may resolve within days or weeks. Continue reading → Brain and Body Impacts of TBI

Continue reading → Brain and Body Impacts of TBI
Posted on | CategoriesHuman Genetics / Pathology / School of Medicine | PI: June L. Round, PhD , Zac Stephens, PhD & Charles Murtaugh, PhD

Microbial Support for Insulin Production

Type 1 diabetes affects more than 2 million people in the United States, many of whom have been managing their disease since childhood. Its symptoms appear after the immune system destroys insulin-producing cells in the pancreas, preventing the body from controlling the amount of sugar in the blood. Continue reading → Microbial Support for Insulin Production

Continue reading → Microbial Support for Insulin Production
Posted on | CategoriesCollege of Pharmacy / Medicinal Chemistry | PI: Katherine Diehl, PhD

Metabolite Biosensors for Live Imaging

The molecules inside our bodies are in constant flux as our cells break down food, produce and store energy, and generate the materials they need to keep us healthy. Amidst this metabolic activity, one particularly influential molecule is acetyl-CoA. Cells depend on acetyl-CoA to produce structural materials, signaling molecules, and energy… Continue reading → Metabolite Biosensors for Live Imaging

Continue reading → Metabolite Biosensors for Live Imaging
Posted on | CategoriesHuman Genetics / Internal Medicine | PI: Jihyun Song, PhD & Josef Prchal, MD

High-Altitude Adaptation Provides Insights into Blood Cancer Care

For people with the rare blood cancers polycythemia vera and essential thrombocythemia, inflammation is common, widespread, and problematic. Chronic inflammation increases the risk of developing blood clots, putting people at risk for heart attacks, stroke, or pulmonary embolism. It also drives the progression of the cancer itself. Continue reading → High-Altitude Adaptation Provides Insights into Blood Cancer Care

Continue reading → High-Altitude Adaptation Provides Insights into Blood Cancer Care
Posted on | CategoriesBiochemistry / School of Medicine | PI: Eric W. Schmidt, PhD & Christopher P. Hill, DPhil

Adopting Nature’s Chemistry

High atop mountains and deep in the sea, animals make molecules that help them thrive in their ecological niches. Many of them make good medicines. But when it comes to getting medicines based on natural products to patients, it’s not usually practical to retrieve enough of a natural compound from the organism in which it was first found to enable drug development and testing. Scientists must find a way to scale up production. Continue reading → Adopting Nature’s Chemistry

Continue reading → Adopting Nature’s Chemistry
Posted on | CategoriesPopulation Health Sciences / School of Medicine | PI: Elissa Ozanne, PhD

Shared Decision Making Strategies for Stroke Prevention

Millions of people in the United States live with atrial fibrillation (AFib), an abnormal heart rhythm that causes blood to pool in the heart, where it can form clots that can cause stroke. This risk can be significantly reduced by taking anticoagulant medications. There are several options to reduce the likelihood of blood clots but each has drawbacks… Continue reading → Shared Decision Making Strategies for Stroke Prevention

Continue reading → Shared Decision Making Strategies for Stroke Prevention